New Ascra at T2

For the best disease control and biggest yields

Buy Bayer, invest in your future success

The development of Ascra is just one example of the investment made by Bayer in the future of farming. For every £10 you spend on Bayer products, at least £1 goes into research and development.

It means you aren’t just buying an answer for today’s problems, you’re investing in the future of British and Irish farming by supporting the discovery, research and development of solutions for tomorrow’s challenges.

What will Ascra mean for you?

The biggest yields
Delivering 0.3t/ha more than Adexar*

Best Septoria control
6% better control than Adexar on L1 & L2*

Increased profitability
£40/ha EXTRA margin over Adexar*

Greater flexibility
Longer application windows without drop off in performance

Peace of mind
Delivering yield whatever the weather.


The best azole
Performance has separated from epoxiconazole

Ascra delivers 80% azole dose at 1.2 L/ha
Minimum needed for effective Septoria control at T2

Broadest spectrum activity of any azole
Septoria, rusts, eyespot, mildew and fusarium

The best alternative mode of action to protect SDHIs
Works with the SDHIs inside the leaf


A leading second generation SDHI
Proven performance in Aviator

Excellent Septoria and rust control
Powerful long-lasting activity

Delivers a physiological crop boost
Increase yield in the absence of disease

The best alternative mode of action to protect azoles
Works inside the leaf like azoles


The first SDHI in the benzamide class
Complements activity of bixafen

Fast translocation through the leaf Enhances curativity against Septoria

Different resistance spectrum to other SDHIs Controls different spectrum of Septoria strains*

Enhances bixafen’s physiological crop boost
Brings greater benefits, for example on increased rooting


Formulation EC

Active ingredients 65g/L bixafen + 65g/L fluopyram +130g/L prothioconazole

Crops Wheat

Dose 1.2-1.5 L/ha

Diseases Septoria, yellow rust, brown rust, mildew, eyespot, fusarium and tanspot

Maximum treatments 2

Maximum individual dose 1.5 L/ha

Maximum total dose 3.0 L/ha


Latest time of application GS61

What do you need from a T2 fungicide?

Widely quoted studies show that 70% of wheat yield comes from keeping the top two wheat leaves free from disease for as long as possible to allow maximum photosynthesis during grain fill. So what attributes should you be looking for from your T2 fungicide?

• Excellent disease control – particularly of Septoria, but also covering other disease threats
• Curativity for kickback to clear up any disease already in leaf two
• Persistency to last through to grain fill
• Consistency in performance whether it rains or shines
• Easy application – minimise the number of cans to use and quickly rainfast to ensure area covered efficiently in disruptive weather.

Disease control with Ascra

The unique properties of Ascra means that it is ideally suited to the T2 timing in winter wheat. Its ability to control Septoria and deliver outstanding yield benefits gives growers unrivalled protection for their crops and increased profitability.

Ascra boosts disease control, especially Septoria, to new levels thanks to the strong azole backbone of prothioconazole and the combination with two SDHIs in bixafen and fluopyram. The latter makes the difference – increasing curativity and bringing extra consistency – meaning performance reaches a new standard.

What does fluopyram bring?

Source: 41 Independent and Bayer trials 2012, 14, 15 & 16.

Source: 41 Independent and Bayer trials 2012, 14, 15 & 16.

Fluopyram is a fast-acting SDHI, distributed faster through the leaf than existing SDHI chemistry. This immediate availability increases control of latent disease in the leaf – improving curativity – and creating a product which gives not only better control of Septoria on average, but more consistent control too.

Backed by the only true primary azole – prothioconazole

Source: 4 Independent trials 2016.

Source: 4 Independent trials 2016.

Trials in the past couple of seasons have proven that prothiconazole is now in a class of its own against Septoria in the UK, consistently outperforming epoxiconazole and metconazole. This means the SDHIs in Ascra have comparatively less work to do in controlling Septoria than competitor products, creating a more sustainable level of disease control.

How does it compare to Adexar?

Source: 2 Independent trials 2015 and 2016, Germany.

Source: 2 Independent trials 2015 and 2016, Germany.

Ascra brings a new level of disease control to wheat flag leaf fungicides, and that difference is only increased as the need for curativity increases. In this trial, where Ascra and Adexar were sprayed 1, 3, 6 and 9 days after plots were inoculated with Septoria, there was a clear difference in control and yield from full rates of both Ascra and Adexar.

Getting the best from Ascra

Ascra belongs at T2
The extra curativity in Ascra, as well as its superior disease control and yield protecting qualities, makes it ideally suited to the flag leaf timing, where you need to protect the yield-generating leaves and take out any latent disease present in leaf two.

Apply it in a robust programme, preferably including a T0 where appropriate, and following Aviator at T1 for best results and to help slow resistance development.

The rate is important
Typically apply at 1.2L/ha – this dose provides the 80% dose of prothioconazole to provide the strong backbone required for Septoria control, and activity on other diseases, such as rusts, mildew and fusarium, while applying an appropriate dose of SDHI chemistry.
Full yield-building activity is not generated at less than 1.2L/ha, but in high disease pressure situations or where applications have been delayed significantly, increase to the full rate of 1.5L/ha to maximise eradicant activity.Flexible timingTiming is crucial for getting the best out of fungicides with reducing curativity, and Ascra doesn’t change that fundamentally. The best timing will remain full flag leaf emergence, but if weather goes against you at this key time, then rest assured that Ascra is your best option because of its enhanced curativity to maintain as much yield potential as possible even if delayed.
Can I mix with multi-sites, such as chlorothalonil?
Yes, you can mix multi-sites with Ascra at T2, however, they remain most beneficial earlier in the programme at T0 and T1.

Excellent disease control is translated into the biggest yields with Ascra. Typically in trials Ascra has given around 0.3 t/ha on average over current competitors at T2 – worth around £40/ha extra margin to growers.

Top performance in 2016 AICC T2 trials

In five AICC trials, where a combination of diseases were present, Ascra was the top performing fungicide in each one producing around 0.4-0.5t/ha extra yield over equivalent rates of Adexar.

Ascra flexibility and curativity

In three independent trials, investigating T2 timings, again Ascra outperformed the competition consistently, both at the perfect T2 timing and when delayed.

How does it compare to Adexar?

Across 5 contrasting seasons, Ascra has yielded more than Adexar in nearly 70% of trials. Which one do you want to use this season?

Judge Ascra for yourself

How it worked

In 2016 we asked 42 farmers to compare their standard T2 fungicide treatment with 1.5L/ha of Ascra. That’s it – we didn’t specify what that treatment needed to be, or what programme they used at other timings, because we were confident that Ascra would live up to its potential we had seen in our trials.

The growers were asked to put the different treatments over a weighbridge, and send us the results.

James Price

We got a good result - 0.3 t/ha yield increase from using Ascra which is fantastic. We would definitely use Ascra again, it’s a product that’s worked for us this year. With that sort of yield increase it’s a no brainer to use it again.

David Hoyles

Our Judge for Yourself result came in at 11.66 t/ha this year. That was more than the Yield Enhancement Network (YEN) plot in the same field (11.29 t/ha), which also had extra nutrition compared with the Ascra plot. The extra Ascra yield would have been worth around £30-40/ha.

Simon Beddows

The Judge for Yourself result this year was pleasing, we got 0.4 t/ha increase over the farm standard worth about £60/ha. If we could have got that increase across all of our 300 hectares of winter wheat this year that would have been a nice lump of money to put into the bank.

Biggest Yields with Ascra - Growers
Ascra yielded more than the standard T2 treatment of our 42 Judge for Yourself farmers in 70% of the trials. On average that equated to 0.3 t/ha more yield.

70% of farmers who tried Ascra in 2016 improved their yields

Source: 42 Independent grower trials 2016.

How Ascra helps combat resistance development

With three active ingredients Ascra is able to effectively attack Septoria through two modes of action. Prothioconazole is a DeMethylation Inhibitor (DMI), which works by disrupting production of the building blocks of the cell wall, so the cell collapses and dies.

Both bixafen and fluopyram are Succinate DeHydrogenase Inhibitors (SDHI). These effectively block the energy supply to the cell from the mitochondria.

Crucially, bixafen and fluopyram are slightly different types of SDHI. Bixafen is pyrazole-carboxamide, while fluopyram is a benzamide. This means that they have slightly different binding patterns, which can help overcome some changes in the binding site caused by mutations.

In laboratory tests, where mutations in the SDHI binding site have been artificially created in Septoria, the combination of the two SDHIs has given control of a broader range of isolates. But the high rate of prothioconazole in the product is key for resistance management, not having two complementary SDHIs.

Protecting SDHI and azoles is vital

We all know that curativity of azole fungicides against Septoria has reduced in recent years, thanks to the multitude of mutations that have developed in the CYP51 enzyme the fungicide binds to.

Similarly there have been warning signs of resistance development to SDHI fungicides with the occasional discovery of Septoria with mutations in the binding site of SDHI fungicides.

It is important that we look after both types of chemistry – both will be backbones for wheat disease control programmes for years to come, providing we can slow resistance development.

Laboratory study of SDHI cross-resistance pattern on selected Septoria mutants

The graph shows the relative performance of different SDHIs against strains of Septoria created in the laboratory with mutations to the SDHI binding site. Green indicates complete control of Septoria by an SDHI, while red suggests performance is impaired. Colours in between indicate intermediate performance. The tests have shown that bixafen and fluopyram have complementary performance against this range of strains, and could give broader control of Septoria in field situations if these isolates develop singularly

Greener leaves

Xpro products can increase the chlorophyll content / photosynthesis in leaves making them bigger, healthier and greener for longer. This allows the plant to provide yield building energy during the critical grain fill period, and yield increases above that from disease control alone.

Bigger roots

In field trials Ascra treated plants have increased root diameter compared with other treatments, both in the top soil and at depth. This indicates the potential of Ascra treated crops to scavenge nitrogen and other essential nutrients more effectively after T2 application.

Hardier plants

In addition to the larger roots in Ascra treated crops, which could make the plants more resilient to drought stress, other field trials have indicated that Ascra treated crops have higher water use efficiency. This means that less water is required to produce a yield gain, crucial in drought years. In drought conditions Ascra yielded 0.74 t/ha more than Adexar, and with sufficient water 0.34 t/ha more than Adexar both in low disease situations.

Easy spraying

The Leafshield formulation enhances Ascra’s application ensuring the product sticks to the leaf on contact before spreading over the leaf to provide the most efficient delivery of disease control benefits.

Protected investment

The Leafshield formulation in Ascra brings the same super-quick rainfastness of just minutes as all the other Xpro formulations. This means growers can capitalise on tight spray windows knowing their investment in Ascra is protected even if it rains within minutes of spraying.

Better coverage

Ascra droplets spread more than competitors, such as Adexar, in spray coverage tests at Silsoe Spray Applications Unit. This high coverage means less chance of disease escape as well as uniform distribution in the leaf, and confidence to use different application techniques, such as air induction nozzles or lower water volumes.